PDRN | The Salmon Sperm Facial
Polydeoxyribonucleotide (PDRN) therapy, also known as the Salmon Sperm Facial, is an advanced regenerative skincare treatment that uses purified salmon-derived DNA to deeply hydrate, repair, and revitalize the skin. At Forbidden Well, we apply high-purity PDRN formulations to support cellular renewal, enhance elasticity, and restore radiant vitality with exceptional precision. This treatment delivers measurable results by boosting fibroblast activity, accelerating collagen synthesis, strengthening the extracellular matrix, and dramatically improving hydration and skin repair, making PDRN one of the most potent regenerative skincare technologies available. With no synthetic additives and minimal downtime, PDRN is an elegant solution for those seeking refined, resilient, and scientifically advanced rejuvenation.
WHY CLIENTS TRUST OUR PDRN APPROACH
At Forbidden Well, our approach to regenerative skincare is grounded in precision, science, and uncompromising quality. PDRN is not a trend. It is a clinically supported bioactive compound shown to enhance collagen pathways, accelerate cellular repair, and dramatically improve skin hydration. We use only high-purity, pharmaceutical-grade PDRN and apply it with meticulous technique to ensure optimal penetration and measurable results. Every PDRN session is fully customized. Our team evaluates your skin’s structure, hydration levels, and cellular activity to deliver treatment exactly where it is needed. No shortcuts. No one-size-fits-all protocols. Each service is performed by trained professionals who understand the anatomy of the skin and the nuances of regenerative science. The outcome is elevated yet natural: smoother texture, improved elasticity, and a radiant complexion that looks refreshed, not altered.
NATURAL REGENERATION. REFINED RESULts.
- Every skin has the capacity to renew itself, and with PDRN, we help it function at its highest level. Using pharmaceutical-grade PDRN and precise, science-backed application, our specialists deliver bioactive compounds exactly where they have the greatest regenerative impact. The result is a powerful increase in fibroblast activity, collagen production, and moisture retention that leaves the skin smoother, firmer, and noticeably more radiant. No synthetic fillers. No harsh resurfacing. No overdone look. Just your skin performing better than ever: Hydrated, refined, and naturally restored with elevated precision.
New Client Special - Radiance Starter
$50 off
Your First PDRN Treatment with us
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New Client PDRN Offer:
This promotion includes $50 off your first PDRN treatment with a qualifying purchase. A qualifying purchase refers to any PDRN treatment performed during your first visit to Forbidden Well. The $50 discount will be applied toward your total treatment plan during the same session. This offer has no cash value and may not be transferred, split across visits, or banked for future use.
Please note: Discount must be applied at the time of your first treatment. This promotion cannot be combined with other discounts, offers, packages, or events unless explicitly stated in writing by a Forbidden Well representative. This offer is subject to availability and may be discontinued or modified at any time without notice.
All PDRN treatments are performed by licensed estheticians trained in advanced skin physiology, and professional-grade regenerative skincare protocols. While our team is committed to delivering safe, effective, and naturally refined results, individual outcomes may vary based on skin condition, hydration levels, lifestyle factors, and overall skin biology. No treatment can guarantee identical or permanent results. A consultation is required to determine candidacy for PDRN related services.
For questions about this treatment, your eligibility, or general policies, please contact us directly. We are here to help.
Treatment Pricing
Full Face
This advanced treatment combines professional microneedling with a pharmaceutical-grade PDRN (salmon DNA) infusion to deliver visibly firmer, smoother, deeply hydrated skin. The microneedling process creates controlled micro-channels that allow high-purity PDRN to penetrate more effectively, boosting fibroblast activity, enhancing collagen synthesis, and accelerating cellular repair. Ideal for clients seeking improved texture, elasticity, and long-lasting radiance, this treatment offers a powerful regenerative upgrade far beyond standard microneedling alone.
Treatable Areas
Full Face Rejuvenation, Under-Eyes (tear trough region), Cheeks, Nasolabial Folds, Marionette Lines, Jawline, Acne Scars, Surgical Scars, Stretch Marks, Neck (crepey skin), Décolletage
Need Help?
Meet with one of our expert providers for a complimentary consultation.
WHAT TO EXPECT AT YOUR FIRST VISIT
From consultation to results, your experience at Forbidden Well is built around personalization. Our team will guide you through every step — from targeted skin assessment and treatment planning to professional PDRN microneedling application and post-care guidance. You’ll leave feeling informed, confident, and empowered.
Options. Select what works for you.
Not sure if this treatment is right for you? Our expert team at Forbidden Well will guide you through a personalized consultation to determine the best approach for your goals. Every new client experience includes a curated welcome kit as part of your first visit.
HOW PDRN THERAPY WORKS AT FORBIDDEN WELL
Want to restore radiance, boost hydration, and rejuvenate your skin at a deeper cellular level? PDRN (Polydeoxyribonucleotide), also known as salmon DNA extract, is a clinically supported regenerative compound that enhances collagen pathways, accelerates skin repair, and strengthens the extracellular matrix. When paired with professional microneedling, PDRN absorbs more effectively, making this treatment one of the most powerful non-invasive solutions for refined, luminous, and resilient skin across all skin types and tones.
Ideal For:
✓ Improving skin texture & elasticity
✓ Enhancing hydration & barrier strength
✓ Softening fine lines & early aging
✓ Reducing acne scars & textural irregularities
✓ Restoring radiance and overall skin vitality
Not Intended For:
✘ Immediate volume restoration (use fillers)
✘ Treating deep skin laxity without adjunctive therapy
✘ Active acne, infections, or inflammatory skin conditions
Skin Rejuvenation
PDRN is applied topically during microneedling, allowing the bioactive molecules to penetrate through micro-channels in the skin. This activates fibroblasts, increases collagen and elastin production, improves texture, boosts hydration, and enhances overall skin vitality. It’s ideal for addressing fine lines, dullness, crepey skin, acne scars, and early signs of aging.
Texture & Elasticity Repair
By supporting cellular turnover and boosting the skin’s natural repair mechanisms, PDRN helps smooth uneven texture, reduce the look of scars, improve elasticity, and strengthen weakened or dehydrated areas of the skin. This makes it an excellent choice for clients seeking firmer, tighter, more youthful-looking skin without invasive procedures.
Deep Hydration & Barrier Support
PDRN’s hydrophilic properties attract and retain moisture within the skin, improving suppleness and reducing dryness-associated fine lines. The treatment reinforces the skin barrier, enhances resilience against environmental stressors, and leaves the complexion visibly plumper and more radiant.
How It Works
Step 1: Consultation & Mapping
Your treatment begins with a consultation, where your provider will walk you through your treatment areas and to map out where the neuromodulators will be injected.
How It Works
Step 1: Consultation & Mapping
Your treatment begins with a consultation, where your provider will walk you through your treatment areas and to map out where the neuromodulators will be injected.
How It Works
Step 1: Consultation & Mapping
Your treatment begins with a consultation, where your provider will walk you through your treatment areas and to map out where the neuromodulators will be injected.
PDRN MICRONEEDLING – WHAT TO KNOW AT A GLANCE
Before Your Treatment
- Wait at least 2 weeks Wait at least 2 weeks after major facial treatments (chemical peels, lasers, strong resurfacing).
- Pause Supplements & Active Skincare Avoid fish oil, vitamin E, retinoids, exfoliants, and acids for 3–5 days before your treatment, unless otherwise instructed.
- Arrive hydrated + Nourished Well-hydrated skin absorbs PDRN more effectively and improves treatment comfort and results.
AFTER YOUR TREATMENT
Avoid touching the skin or applying makeup for 12–24 hours. Mild redness or pinpoint bleeding is normal for 24–48 hours. For the next 24–48 hours, avoid:
Workouts
Sun exposure
Saunas / steam rooms
Alcohol
Do not use retinoids, acids, or exfoliants until cleared by your provider. Avoid direct heat for several days and resume SPF once skincare is allowed.
WHEN TO EXPECT RESULTS
Most clients notice a hydrated, smoother glow within 3–5 days. Skin continues to improve over the next 2–4 weeks as collagen synthesis increases. Texture becomes more refined, fine lines soften, and the complexion appears more radiant and even.
Results typically peak around 4–6 weeks, with monthly or quarterly treatments recommended for optimal rejuvenation.
Advanced Cellular Regeneration
PDRN works at a deep cellular level to activate the skin’s natural repair pathways, increasing fibroblast activity and accelerating tissue regeneration. This powerful bioactive compound delivers targeted healing to areas affected by texture irregularities, environmental damage, and early aging signs. Over a series of treatments, the skin becomes stronger, healthier, and more resilient, with a noticeable improvement in firmness and overall vitality.
Collagen & Structural Renewal
PDRN has been clinically shown to stimulate Type I collagen synthesis, helping rebuild the skin’s foundational support structure. This results in tighter, lifted, and more elastic skin over time. By enhancing dermal thickness and restoring youthful spring, PDRN provides long-lasting regenerative benefits without altering facial expression or adding artificial volume. Fine lines soften, firmness increases, and the skin’s overall architecture improves naturally.
Hydration Optimization & Barrier Strengthening
PDRN significantly improves moisture retention by reinforcing the skin’s natural barrier and reducing transepidermal water loss. This leads to plumper, dewier, more hydrated skin from the inside out. As barrier function strengthens, redness, sensitivity, and irritation decrease. The skin becomes smoother, more supple, and better equipped to protect itself against environmental stressors and daily wear.
Skin Texture Refinement & Scar Recovery
Because PDRN enhances cellular turnover and stimulates tissue remodeling, it is highly effective for softening acne scars, surgical scars, and uneven texture. Over time, the skin surface becomes more refined, polished, and even. PDRN supports collagen reorganization within scar tissue, helping the skin heal in a healthier pattern while reducing the appearance of irregularities and past damage.
Radiance Enhancement & Complexion Balancing
PDRN promotes clearer, more luminous skin by reducing inflammation and supporting healthy cellular function. Uneven tone, dullness, and discoloration gradually fade as the skin becomes brighter and more uniform. With improved circulation and increased cellular energy, the complexion appears naturally radiant. Become restored with a youthful glow and greater clarity.
Gentle, Safe, and Compatible With All Skin Types
PDRN is non-sensitizing, making it suitable for sensitive, reactive, and diverse skin tones without downtime or aggressive disruption. Because it works with the body’s natural healing processes, it delivers results safely and gradually. This makes PDRN one of the most versatile regenerative treatments available with consistent benefits whether your skin is dry, oily, mature, acne-prone, or combination.
Frequently Asked Questions
What exactly is PDRN (Salmon Sperm Extract)?
PDRN, or Polydeoxyribonucleotide, is a highly purified DNA molecule derived from salmon. It is known for its regenerative, collagen-stimulating, and deeply hydrating properties. When applied during microneedling, PDRN penetrates through micro-channels in the skin and supports fibroblast activity, tissue repair, and improved elasticity. At Forbidden Well in New York, we use pharmaceutical-grade PDRN to ensure maximum safety, purity, and visible improvement in texture, hydration, and radiance.
How does PDRN Microneedling work?
During PDRN microneedling, controlled micro-channels are created in the skin to allow high-purity PDRN serum to penetrate deeply and perform its regenerative work. The micro-injuries stimulate your body’s natural healing response, while the PDRN floods the skin with nucleotides that encourage cellular repair, collagen synthesis, increased hydration, and strengthened skin barrier function. Together, this dual-action approach improves skin tone, texture, elasticity, fine lines, scars, and dullness far more effectively than microneedling alone.
What’s the difference between PRP and PDRN?
PRP uses your own blood platelets to stimulate collagen and tissue repair. PDRN, on the other hand, is a potent bioactive compound extracted from salmon DNA that works at a deeper cellular level by increasing fibroblast growth, repairing damaged skin structures, and boosting hydration. PRP is best for overall rejuvenation, hair restoration, and healing.
PDRN is superior for elasticity, hydration, smoothing texture, scar improvement, and strengthening the skin barrier.
At Forbidden Well in Union Square NYC, we exclusively use PDRN as an add-on to microneedling for enhanced anti-aging and regenerative results.
What skin concerns does PDRN help with?
PDRN is effective for improving fine lines, dullness, acne scars, enlarged pores, crepey skin, texture irregularities, early aging, redness, and dehydration. It is also used to strengthen thin or fragile skin, support post-inflammatory healing, and enhance collagen rebuilding. Because PDRN repairs the skin barrier, it is especially helpful for clients who experience dryness, sensitivity, or low elasticity.
Is PDRN Microneedling painful?
Most clients tolerate the treatment very well. A professional-strength numbing cream is applied beforehand, significantly reducing discomfort. You may feel a light scratching or pressure sensation throughout the session. Afterward, mild redness or sensitivity is normal for 12–24 hours, but discomfort is generally minimal compared to more aggressive laser treatments.
How long do results last?
Results typically last 6–12 months depending on skin quality, age, lifestyle, and how well the skin is maintained afterward. Monthly or quarterly maintenance sessions are recommended for optimal long-term collagen and hydration support.
Who is a good candidate for PDRN Microneedling?
PDRN is suitable for all skin types and tones, including sensitive or compromised skin. It’s ideal for anyone seeking non-invasive rejuvenation, improved hydration, smoother texture, collagen support, or accelerated skin repair. Clients with active infections, pregnancy, or certain medical conditions should undergo a consultation prior to treatment.
Is there downtime after PDRN Microneedling?
Downtime is minimal. Expect redness for 12–24 hours and slight sensitivity for up to 48 hours. Most clients return to work the next day. Makeup can usually be applied after 24 hours, and full skincare routines can resume once the skin is no longer sensitive.
Can PDRN be combined with other treatments?
Yes. PDRN pairs exceptionally well with LED therapy, chemical peels, hydrafacials, and even PRP for enhanced regenerative benefits. Your provider will guide you on safe treatment sequencing to maximize results without overstimulating the skin.
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Curated by Forbidden Well™
What Our Clients Are Saying
“I’m super particular about my face, so I was a little hesitant to try anything at first—but after one visit to Forbidden Well, I was hooked. I saw Jake (not the owner, but honestly he might as well be with how good he is) and we did a lip flip, and a baby tweak around my eyes to soften the squint lines. He knew exactly what would enhance my features without changing them. Everything looks so natural—like I just got 10 hours of sleep and a facial, but better. The space is stunning, the energy is elevated, and it just feels good being there. Forbidden Well is 100% my new go-to.”
There’s something really special about Forbidden Well. I’ve been around a lot of wellness spaces, but this one just hits different—the energy, the people, the attention to detail. It’s tucked right by Union Square but feels like a retreat the second you walk in. I recently had wrinkle relaxers done on my forehead and jawline, and the results are so natural. No one can tell I had anything done, but I’ve been getting compliments nonstop about how ‘rested’ I look. It’s exactly what I was hoping for—clean, refined, and still completely me.
“As a model, subtlety is everything—I need to look fresh without ever looking ‘done.’ It was my first time trying Botox and I couldn’t have asked for a better experience than what I had at Forbidden Well. The space is gorgeous, the vibe is calm and elevated, and everyone made me feel completely comfortable. I saw Jake (not the owner lol), and he was incredible. We did a baby brow lift, a tiny bit in the chin to smooth out dimpling, and a soft lip flip—and the results are exactly what I hoped for. Just a slightly more refined version of me. Jake’s precision and eye for detail are next level. I’ll definitely be coming back.”
