What It Is
PDRN is a regenerative skin treatment derived from highly purified salmon DNA fragments, designed to support skin renewal, collagen response, and overall skin quality.
At Forbidden Well, PDRN is delivered with microneedling so the treatment reaches where it matters most. The result is a skin-focused protocol aimed at smoother texture, better glow, improved resilience, and a more rested overall appearance.
Why Clients Choose PDRN
No Blood Draw Required
Unlike PRP, PDRN does not require a blood draw and offers a more standardized treatment input from session to session. It is especially appealing to clients who want regenerative skin work with a cleaner, more streamlined treatment experience.
The aesthetic value of PDRN is that the skin can look healthier, smoother, and more refined without looking treated in an obvious way. It reads as better skin, not more product.
Ideal Candidates
In-studio appointments at Forbidden Well. Consultation included with your first session.
Results Gallery
Treatment Imagery
PDRN preparation
Microneedling application
Treatment close-up
Post-treatment glow
Results at 2 weeks
Skin texture detail
The Process
How PDRN Works
Consultation
Your provider reviews skin history, treatment goals, sensitivities, and whether PDRN is the right regenerative option for your face.
Prep & Numbing
Skin is cleansed and a topical numbing agent is applied for comfort.
PDRN Microneedling
Microneedling creates controlled micro-channels while pharmaceutical-grade PDRN is delivered across the treatment area.
Recovery & Aftercare
Skin is soothed, protected, and you leave with a detailed aftercare plan. Mild redness is expected initially and generally settles quickly.
Visual Results
Before & After
Texture Refinement — 3 Sessions
Before
After
Dullness & Glow — 2 Sessions
Before
After
Investment
Pricing
Regenerative Microneedling
PDRN Facial
$450
per session
Package: 3 sessions for $1,200
Frequently Asked Questions
PDRN stands for polydeoxyribonucleotide. It is a regenerative skin treatment derived from salmon DNA that supports cellular repair, hydration, and tissue regeneration when delivered into the skin.
PDRN is delivered via microneedling, which creates micro-channels in the skin to allow deep penetration of the active ingredient. This combination accelerates skin renewal and maximizes the regenerative effect.
PDRN is particularly effective for skin repair, deep hydration, fine lines, dullness, loss of elasticity, and post-inflammatory recovery. It is one of the more advanced regenerative options available at Forbidden Well.
Yes. PDRN is derived from salmon DNA, which is why it is sometimes referred to as the salmon sperm facial. The active compound is a highly purified polynucleotide extract, not whole genetic material.
Numbing cream is applied before the session. The microneedling component causes minor sensation but is well tolerated by most clients.
A full PDRN with microneedling session takes approximately 60 to 90 minutes including preparation and numbing time.
A series of three to four sessions spaced three to four weeks apart is recommended for optimal results. Single sessions are available but a series produces more significant and lasting improvement.
Expect redness and mild sensitivity for 24 to 48 hours following treatment. Avoid direct sun exposure, active skincare ingredients, and makeup for at least 24 hours post-session.
PDRN stands for polydeoxyribonucleotide. It is a regenerative skin treatment derived from salmon DNA that supports cellular repair, hydration, and tissue regeneration when delivered into the skin.
PDRN is delivered via microneedling, which creates micro-channels in the skin to allow deep penetration of the active ingredient. This combination accelerates skin renewal and maximizes the regenerative effect.
PDRN is particularly effective for skin repair, deep hydration, fine lines, dullness, loss of elasticity, and post-inflammatory recovery. It is one of the more advanced regenerative options available at Forbidden Well.
Yes. PDRN is derived from salmon DNA, which is why it is sometimes referred to as the salmon sperm facial. The active compound is a highly purified polynucleotide extract, not whole genetic material.
Numbing cream is applied before the session. The microneedling component causes minor sensation but is well tolerated by most clients.
A full PDRN with microneedling session takes approximately 60 to 90 minutes including preparation and numbing time.
A series of three to four sessions spaced three to four weeks apart is recommended for optimal results. Single sessions are available but a series produces more significant and lasting improvement.
Expect redness and mild sensitivity for 24 to 48 hours following treatment. Avoid direct sun exposure, active skincare ingredients, and makeup for at least 24 hours post-session.
Union Square, NYC
Better Skin, Not More Product
Book your consultation and let us build a regenerative skin plan around PDRN, PRP, or a more complete treatment sequence based on your goals.
Book Your PDRN TreatmentExplore our skin & facial treatments or PRP therapy
What Our Guests Say
I was skeptical about PDRN but the results speak for themselves. After two sessions, my skin is visibly firmer, my pores are smaller, and I have this luminous quality that I’ve never achieved with any other treatment. My dermatologist even noticed the difference.
Sophia T.
March 2026
